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Avanafil, marketed as Stendra, is a second-generation PDE5 inhibitor characterized by high selectivity for phosphodiesterase type 5 compared to other isoenzymes. Its rapid onset of action is linked to fast absorption and a Tmax of approximately 30 to 45 minutes. The drug undergoes hepatic metabolism through CYP3A4, generating inactive metabolites. Within this pharmacological context, buy stendra uk denotes a compound with accelerated absorption and favorable selectivity ratios.